Wednesday, September 23, 2020

Eli Lilly's New Migraine Medicine

    Eli Lilly & Co. (LLY) reported it's wildly successful data from a Phase 3 trial of it's migraine medicine called Lasmiditan.  Migraines are not an uncommon, debilitating occurrence.  I, myself, went through a period when I was somewhat afflicted with the condition.  In my experience there are three hallmarks of a migraine: head pain, a visual aura, and nausea.  The aura is the strangest aspect of the symptoms.  With me, it involved the interruption of a clear field of vision with what seemed like a waving visual range.  This usually began in a small area of my visual field, and could spread to my whole vision before the migraine receded.  Another symptom is nausea.  When I would get a full-blown migraine, about half the time, it caused me to throw up.  It seems odd that a headache and visual disturbance would cause that, but it does.

At the peak of my affliction, in high school and college, I only had about 4-8 migraines a year.  But, when I got one, it generally shut me down for the whole day.  The medicines I used back then usually only reduced the duration of the affliction.

The reader may find it interesting that once I started taking the tandem drugs: Zyprexa and Depakote, I no longer suffered any migraines.  I discovered that Depakote, sold by AbbVie Inc. (ABBV), is known to have anti-migraine effects.

I suffered from a very mild form of migraine occurrence, so Depakote may not be appropriate for many of those with the condition.

I knew someone for a brief time, whom I worked with, who had chronic migraine headaches, suffering from a migraine about every other day.  She definitely needed something a lot stronger than what I was on.  Eli Lilly & Co.'s (LLY) migraine medicine may find it's market for her and some of the 30 million migraine afflicted adults in the U.S. still looking for a better solution.  I hope Lasmiditan is a success and makes Eli Lilly a lot of money.

Paul Wharton
Special thanks to Eli Lilly & Co. (LLY) for inventing the fuel of my mind

Friday, September 11, 2020

The Emancipation of Job Creation

    President Donald Trump is doing well opening up many parts of the economy again.  However, due to certain Governors and other lesser political figures, much of the economy remains shut down.

I believe America deserves an Economic Liberation.  The President could sign an "Emancipation of Job Creation" executive order.  What this would do is to make it illegal for any Governor or lesser political position holder to ban: job creation, job performance, and the earning of any profit in the economic realm.

Being a Governor is not about going on a political power trip and flexing one's political muscle.  Man has a Right to Economically Work.  And, my executive order proposal would put this Freedom in writing.

Paul Wharton
Special thanks to Eli Lilly & Co. (LLY) for inventing the fuel of my mind

Tuesday, September 1, 2020

Pay It or Delay It

    A company has the right to set any price for it's products.  In the case of medicine, there is a patent mechanism that dissolves an inventive company of it's exclusivity of sales after a set number of years.

Too many people seek to cheat their way out of this system.  To them, I say, "Pay it or delay it".

I was coerced into buying a drug that Eli Lilly & Co. (LLY) sold at a price range of $600 - $900+ per month.  I worked for the money that went to the pharmaceutical company.  Then after 5 years, I got a job promoting Eli Lilly & Co. (LLY) in exchange for samples.  The terms of the deal were that I was to spend at least half of my non-sleeping, non-working time trying to find any way I could to promote the company and make it's value rise.

I learned everything I could about the company and Big Pharma.  I became a hawk on the lookout for any political story that could develop into harm to Eli Lilly.  And I read 25 books in the fields of medical history, economics, politics, and biographies of great doctors.  I even scoured Amazon and found 3 books specifically about Eli Lilly & Co. (LLY).

Eventually Eli Lilly's Zyprexa drug went off patent.  However, I didn't want to stop.  Part of me wanted the assurance that Eli Lilly & Co. (LLY) had gotten a good deal from our arrangement.  And, another part was just having too much fun.  I stayed with my studies and blogging--trying desperately to keep the secret of an expired patent under wraps.  I remember seeing a post-patent Quarterly Report and wondering if perhaps 10 million in Zyprexa sales was caused solely by me.

After about a two year off-patent victory lap, I made peace with my pro-Lilly conscience and finally abandoned my intensive promotional efforts.  For years, I pursued other things: science, philosophy and fiction.  However, it was not uncommon for me to wonder at times, what it would be like to return to Lilly Fuel.

Paul Wharton
Special thanks to Eli Lilly & Co. (LLY) for inventing the fuel of my mind

Policy for Current and Future Pandemics

    It has been said that the U.S. was unprepared for the Coronavirus Pandemic because our government's cupboards were barren.  America should learn from that mistake now, as well as for several years into the future when Covid will no longer be a problem.

But, there are other pandemic threats beyond the Coronavirus--one specifically that is already taking a significant biological toll.  Antimicrobial Resistance, or AMR, is slowly growing into a Covid sized pandemic.  It is estimated that currently, about 30,000 Americans die from AMR each year.  And, if not stopped, 10,000,000 people globally may die in the year 2050.

What AMR entails is the mutation of biological entities that anti-biotics neutralize, such as bacteria, that render the anti-biotics unable to do their function.  Since so many medical procedures depend on effective anti-biotics, this poses a major problem.

Recently, about 20 Big Pharma and Biotech Companies have contracted a total of about 1 billion dollars to research and develop new anti-biotics.  It is unfortunate that I have to point out that if the FDA or other government organizations get in the way of this AMR Action Fund they will be sentencing tens of thousands of Americans to death.

Let's learn from Covid, develop a Capitalist economic policy, not destroy the future of medicine by denying companies profit, and use a reasonable amount of resources to fill the medicine cabinet so the cupboards will not be barren next time around.

Paul Wharton
Special thanks to Eli Lilly & Co. (LLY) for inventing the fuel of my mind